Severe Acute Respiratory Syndrome

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To the Editor: Qatar had a first wave of infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from March through June 2020, after which approximately 40% of the population had detectable antibodies against SARS-CoV-2. The country subsequently had two back-to-back waves from January through May 2021, triggered by the introduction of the B.1.1.7 (or alpha) and B.1.351 (or beta) variants. 1 This created an epidemiologic opportunity to assess reinfections. Using national, federated databases that have captured all SARS-CoV-2–related data since the onset of the pandemic (Section S1 in the Supplementary Appendix, available with the full text of this letter at NEJM.org), we investigated the risk of severe disease (leading to acute care hospitalization), critical disease (leading to hospitalization in an intensive care unit [ICU]), and fatal disease caused by reinfections as compared with primary infections in the national cohort of 353,326 persons with polymerase-c...

When I was growing up, infectious bovine keratoconjunctivitis (IBK, or pinkeye) in cattle was rather common and relatively easy to treat. An eye patch and a long-acting oxytetracycline injection was often very effective, if IBK was detected early. IBK normally occurs from midsummer through early fall. Calves are typically the most severely affected, as that time of year creates the IBK version of the "perfect storm." Related: Managing most severe form of pinkeye can be difficult Fly populations are at their peak; fly tags administered in April or May are losing their efficacy; the calf's colostral immunity is waning; grasses are maturing, allowing for injury and irritation to the eye; and cattle bunch up under shade, permitting more fly contact among animals. IBK is still rather common, but treatment is not as successful as it once was. The reasons for this poor response to treatment are as complex as the disease itself. It is estimated that IBK costs the bee...

There are several types of medications available to both treat and help prevent severe migraine symptoms. Your treatment options may depend on if you have episodic or chronic migraine, and on the severity and frequency of migraine episodes. Your doctor will discuss your migraine history and the right options for you. In this article, we'll discuss the different types of migraine prevention medications, pros and cons, and how they work. Click on a class of medication to jump to its explanation: If you experience frequent, severe migraine attacks that disrupt your life, your doctor may discuss preventive medications with you. These medications may prevent and treat migraine symptoms but don't cure the condition. Migraine medications are classified into two categories: Abortive medications. Also called acute treatments, abortive migraine medications help manage migraine symptoms as they occur. Preventive medications. These types of medications help lower your risk of having a migr...

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Former wrestler Jimmy Rave has revealed that an MRSA infection in both of his legs has resulted in their amputation. The 38-year-old who wrestled for organizations like Ring of Honor, Total Nonstop Action Wrestling (TNA), and New Japan Pro Wrestling, said in a Twitter post that after experiencing difficultly walking in June he visited doctors who discovered the infection and advised that his legs be immediately amputated. Apparently it's time for me to come clean. This past June I began having trouble walking & went to my surgeon. He determined I had MRSA in both legs & they needed to be amputated immediately. Promoters can tell you along with my peers, I've had a history w/this and would cancel pic.twitter.com/OnU2LgrKQt — Jimmy Rave (@TheJimmyRave) October 24, 2021 The wrestler, whose real name is James Guffey, lost his left arm to infection in October 2020, which forced him to end his 20-plus year wrestling career, Newsweek reported previously. What Is MRSA...

TRICARE is the current health care program in place by the United States Department of Defense's Military Health System. The DoD offers health insurance and benefits for U.S. soldiers, as well as civilian workers, retirees and their dependents, up to 26 years of age, through the TRICARE program. Previously it was known as Civilian Health and Medical Program of the Uniformed Services, or CHAMPUS, but renamed in 1993. Today, it's managed by the DHA, or Defense Health Agency, though prior to 2013 the program was run by Tricare Management Activity or TMA. The DHA was developed specifically to run TRICARE and its operations.  To date, TRICARE covers more than 9 million beneficiaries. Out of the DoD's $50+ billion annual budget, the health care program accounts for 8% of that spend. (That does not include active duty members and TRICARE Prime.)  Types of TRICARE programs TRICARE logo — photo courtesy DVIDS ...